Ray
Charlotte, North Carolina
Daniff puppies for sale
Daniff puppies for sale
$ 600.00
Charlotte, North Carolina
These amazing pups are a mix between an English Mastiff and a Great Dane—often called Daniffs. They’re incredibly intelligent, quick to learn, and already know how to use the dog door! Daniffs make wonderful companions. They’re calm, affectionate, and easy to house train. These pups truly live up to the “gentle giant” name and will grow into loyal, loving fa...
$ 600.00
Romero
Flagstaff, Arizona
75% Great Dane 25% Mastiff
75% Great Dane 25% Mastiff
$ 500.00
Flagstaff, Arizona
We currently have four male and three female puppies that are a mix of 75% Great Dane and 25% Mastiff. They will be ready for adoption in the first week of May. However, please note that these pups will grow up to reaching a height of 6ft, and will require ample attention and exercise. Therefore, we only welcome responsible inquiries. If you need more inform...
$ 500.00
RAMON CARREON
San Bernardino, California
9 Beautiful Daniff Puppies For Sale
9 Beautiful Daniff Puppies For Sale
$ 500.00
San Bernardino, California
Beautiful Daniff Puppies (1st generation Great Dane and Mastiff Mixed Breed) ready for brand new forever home. Mother is full Great Dane and father is full Mastiff. Good homes only. Small rehoming fee. 9 puppies left. 2 males. 7 females. Call or Text Only.
$ 500.00
Caitlyn Crosby
Oklahoma City, Oklahoma
3 male Daniff puppies available
3 male Daniff puppies available
$ 1000.00
Oklahoma City, Oklahoma
We have three CKC-registered male Daniffs that are 50% dane and 50% English mastiff. The parents have undergone genetic health testing, and the puppies are sold with CKC papers, a microchip, shots, and worming. They'll be large canines. The puppy in the last images is from the previous litter. ready by October 15th. Text for more details
$ 1000.00
Judy
Live Oak, Florida
5 Daniff puppies looking for homes
5 Daniff puppies looking for homes
$ 650.00
Live Oak, Florida
We currently have Daniff puppies ready for sale. We offer a variety of 50 Merle shades, as both the parents and grandparents are owned by us. The father is a Merle Great Dane, while the mother is a brindle Mastiff. The available puppies include fawn, fawn Merle, blue Merle, black, and brindle coats. They will come with a Florida certificate of health issued ...
$ 650.00
Judy
Carrollton, Texas
6 beautiful Dannif puppies to good home
6 beautiful Dannif puppies to good home
$ 500.00
Carrollton, Texas
We have six beautiful Daniff puppies to be rehome. They were born on August 22nd. Dad is a brindle English Mastiff. Mom is harlequin Great Dane. Both parents on site, and are family pets. There are 2 males grey with black, 1 harlequin male, and 3 harlequin females. Puppies have been dewormed every two weeks and given their first vaccine. Dew claws have been ...
$ 500.00
Emerson
San Antonio, Texas
Shiann Horner
Rockford, Illinois
Micki
Houston, Texas
Daniff puppies for adoption
Daniff puppies for adoption
$ 800.00
Houston, Texas
Hello, we have a litter of Daniff puppies that were born on October 16. They have had at least 2 vaccines a Neo-parvo and an Imuno-Vac Canine 5. They were wormed every 2 weeks from birth with Nemex2 before they left... They were handled with Toltrazuril a minimum of 2 times. They come with a gift bag... which covers everything you need to get your puppies st...
$ 800.00
Staci
Minnesota, Minnesota
7-Week-Old "Daniff" Puppies for sale
7-Week-Old "Daniff" Puppies for sale
$ 800.00
Minnesota, Minnesota
There are five incredibly cute "Daniff" puppies, a mix of Great Dane and English Mastiff, who are now 7 weeks old. Out of these adorable pups, there are four males and one female. We have a variety of colors to choose from, including brindle and fawn. If you're interested in providing a loving and healthy home for one of these lovely puppies, please don't he...
$ 800.00
Adam
Camden, New Jersey
Daniff puppy looking for new home
Daniff puppy looking for new home
$ 1200.00
Camden, New Jersey
There are 5 Danniff puppies for sale. Dane father and Mastiff mother This will be a pack of large, heavy canines. Currently five weeks old. Puppies with age-appropriate immunizations and a health certificate from a licensed veterinarian will be ready to go on June 24. 1 female Brindle 1 black male 1 black female 1 fawn female with a red mask 1 male in dark f...
$ 1200.00
Jenny
Oklahoma City, Oklahoma
5 Beautiful Daniff Puppies
5 Beautiful Daniff Puppies
$ 1000.00
Oklahoma City, Oklahoma
We currently have lovely Daniff puppies available for adoption! These pups are a mix of Mastiff and Great Dane, with two vet visits already completed. They have also received their dewormer and first round of puppy shots, and their shot record will be provided upon adoption. A rehoming fee will be required. Out of the litter, there are two boys (grey and whi...
$ 1000.00
Micki
Houston, Texas
Daniff puppy looking for new home
Daniff puppy looking for new home
$ 200.00
Houston, Texas
I have to rehome my sweet Daniff puppy who is beautiful and intelligent. She was born on October 16th... That lets her almost 8 months old....but she's still a very cute puppy who will grow until she's at least 2 years old... and she's still very trainable... The mother is a purebred English Mastiff. Her father is a great Dane. She's received all of her baby...
$ 200.00
Gretel
Shelton, Washington
9 weeks old Daniff puppy
9 weeks old Daniff puppy
$ 500.00
Shelton, Washington
Daniff puppies are a wonderful breed, and they make excellent family pets. They are loyal and affectionate, and they require relatively little maintenance. If you’re looking for a large and loving canine companion, then a Daniff might be the perfect match for you. A 9 weeks old Great Dane Mastiff puppy is looking for a new home. This energetic young Daniff p...
$ 500.00
Patricia
Paris, Illinois
Friendly daniff puppy
Friendly daniff puppy
$ 300.00
Paris, Illinois
Friendly daniff puppy, 1 male remaining. Mother is a mantle Great Dane, father is an English mastiff. Only litter. Comes with shot records. Will grow to be X-Large dogs. Rehoming fee is $300. Contact for further details.
$ 300.00
Amos
Corpus Christi, Texas
Daniff puppy
Daniff puppy
$ 300.00
Corpus Christi, Texas
I still have one male daniff puppy available for adoption. He has received his initial vaccinations and is already trained to use puppy pads. If you're interested in learning more about the daniff breed, you can search for it on Google. For additional details, feel free to contact me by phone or text. Please note that there is a rehoming fee of $300.
$ 300.00
Sabrina
Brainerd, Minnesota
Kara
Saint Louis, Missouri
5 Great Dane Bull Mastiff Puppies Left
5 Great Dane Bull Mastiff Puppies Left
$ 500.00
Saint Louis, Missouri
We only have 5 puppies left. 1 boy and 4 girls, all Brindle with the exception of 1 black female. They have received their first vaccinations and have been dewormed twice. The mother dog is a Great Dane, and the father is a Bullmastiff. The parents are members of our family and live with us indoors; the puppies have gotten a lot of attention from my children...
$ 500.00
Jennifer Evret
Bonney Lake, Washington
Daniff puppy fully potty trained
Daniff puppy fully potty trained
$ 1000.00
Bonney Lake, Washington
Hi there! We have one male Daniff puppy available for adoption. There is an adoption fee. He is fully potty trained to go in Alfalfa pellets in our potty area and up-to-date on all vaccines and deworming. He will also have a health check from the vet. Our puppies grow very quickly and this big boy will be around 180-190 pounds when fully grown. If you're int...
$ 1000.00
Daniff Dog Breed Information
The Daniff is a majestic and powerful hybrid dog breed, resulting from the cross between a Great Dane and a Mastiff (typically an English Mastiff). Known for their impressive size, gentle nature, and loyal temperament, Daniffs are gaining popularity as family guardians and affectionate companions. This guide covers everything you need to know about Daniffs—their history, physical traits, personality, care requirements, and what to expect from Daniff puppies.
Origins and History of the Daniff
The Daniff is a relatively new designer breed, developed to combine the best qualities of the Great Dane and the Mastiff. Both parent breeds have ancient roots as protectors, hunters, and working dogs. The Daniff inherits the Great Dane’s elegance and height, alongside the Mastiff’s mass and loyal demeanor.
- Great Dane: Originally bred in Germany as a boar hunter and estate guardian, famous for its height and gentle personality.
- Mastiff: Ancient lineage as a guardian and war dog, renowned for strength, courage, and loyalty.
- Purpose: To create a giant dog with a balanced temperament, suitable for families and guarding.
Physical Characteristics
Daniffs are giant dogs, standing 28–34 inches tall at the shoulder and weighing anywhere from 115 to 200+ pounds. Their appearance reflects both parent breeds—tall and athletic like the Great Dane, but muscular and broad like the Mastiff.
- Coat: Short, dense, and smooth; easy to maintain.
- Color: Fawn, brindle, black, blue, or combinations with white markings.
- Build: Large, muscular, and powerful; deep chest and strong legs.
- Face: Broad head, expressive eyes, and floppy ears.
- Tail: Thick and carried low.
Their sheer size is impressive, but Daniffs move with surprising grace and confidence.
Temperament: Gentle Giant, Loyal Guardian
Despite their intimidating appearance, Daniffs are renowned for their gentle, affectionate nature. They are deeply loyal to their families and often form strong bonds with children and other pets. Their protective instincts are strong, but they are rarely aggressive unless provoked.
- Affectionate: Enjoys cuddling and being close to their family.
- Loyal: Protective without being overly aggressive.
- Gentle: Patient and tolerant, especially with children.
- Calm: Not overly excitable; prefers a peaceful environment.
- Intelligent: Quick learners, though sometimes stubborn.
Daniffs thrive in homes where they are included in daily activities and given consistent attention.
Daniff Puppies: What to Expect
Daniff puppies are adorable, with big paws and playful personalities. Early training and socialization are essential due to their rapid growth and potential for stubbornness. These puppies benefit from gentle, positive reinforcement and exposure to different environments.
Socialization and Training
Introduce Daniff puppies to a variety of people, pets, and settings. Puppy classes are helpful for building confidence and manners. Daniffs respond well to reward-based training but may need patience due to their independent streak.
- Teach basic commands ("sit," "stay," "come") from an early age.
- Use treats, praise, and gentle corrections.
- Leash training is important—adult Daniffs are strong!
Housebreaking and Crate Training
Consistency and routine help with housebreaking. Crate training provides a safe space for rest and helps prevent destructive behavior when unsupervised.
Nutrition
Feed Daniff puppies a high-quality, large-breed puppy food. Proper nutrition is vital to support healthy growth and avoid joint problems. Consult your vet for feeding schedules and portion sizes.
Grooming Needs
Daniffs are low-maintenance in grooming. Weekly brushing keeps their coat healthy and removes loose hair. Bathe occasionally, trim nails monthly, and check ears regularly.
- Brush once a week
- Trim nails monthly
- Clean ears regularly
- Brush teeth for dental health
Living with a Daniff: Everyday Life
Life with a Daniff is peaceful and secure. These dogs enjoy moderate exercise, such as daily walks and playtime, but avoid overexertion, especially in hot weather. Due to their size, Daniffs require ample living space—homes with fenced yards are ideal.
- Exercise needs: Regular walks, gentle play, and mental stimulation.
- Space: Large dogs need room to move and stretch out.
- Companionship: Daniffs dislike being left alone for long periods.
- Travel: Their size means special arrangements for car rides and outings.
Daniffs adapt well to family life and are gentle with children and other pets.
Health and Lifespan
Daniffs are generally healthy but, like all giant breeds, may be prone to certain conditions. Their lifespan is typically 8–12 years. Common health concerns include:
- Hip and elbow dysplasia
- Heart conditions
- Bloat (gastric torsion)
- Joint and bone problems
- Obesity (monitor diet and exercise)
Routine veterinary care, a balanced diet, and regular exercise help ensure a long, healthy life.
Is the Daniff Right for You?
Daniffs are perfect for families seeking a gentle, protective companion with plenty of space. They’re best suited to owners who appreciate large breeds and can provide consistent care and attention. Their calm demeanor and affectionate nature make them ideal for homes with children.
- Perfect for: Families, homes with yards, experienced dog owners, those seeking a gentle guardian.
- Less suitable for: Small apartments, owners unable to handle a giant breed, or those seeking a highly active dog.
Finding a Daniff Puppy: Responsible Adoption Tips
Choose reputable breeders or rescue organizations focused on health, temperament, and socialization. Responsible breeders provide health clearances for both parent breeds and welcome questions.
- Visit breeders in person and ask for health documentation.
- Meet the puppy’s parents and observe their temperament.
- Ask about early socialization and veterinary care.
- Consider adopting from breed-specific rescues or shelters.
Avoid puppy mills and online scams—insist on proper documentation and references.
Frequently Asked Questions about Daniffs
Are Daniffs hypoallergenic?
No, Daniffs are not hypoallergenic, but their short coat sheds minimally.
How much do Daniff puppies cost?
Prices range from $800 to $2,000 depending on breeder reputation and location.
Do Daniffs bark a lot?
They are generally quiet but will bark to alert you to strangers or unusual activity.
Are Daniffs good with kids and other pets?
Yes, Daniffs are gentle and affectionate, making them excellent companions for children and other animals.
How much grooming do Daniffs require?
Minimal—weekly brushing and occasional baths are sufficient.
Fun Facts about Daniffs
- Daniffs can reach heights over 30 inches—towering over many other breeds!
- Their calm nature makes them excellent therapy dogs for families and children.
- Daniffs often inherit the Mastiff’s wrinkled face and the Great Dane’s long legs.
Tips for a Happy Daniff
- Provide gentle exercise and avoid strenuous activity in hot weather.
- Keep up with regular grooming and health checkups.
- Offer plenty of affection and companionship—Daniffs thrive on family bonds.
- Feed a high-quality, large-breed diet and monitor weight.
- Be patient and consistent with training, especially while puppies are growing.
Summary: Why Daniffs Make Wonderful Family Companions
The Daniff is a gentle giant with a loving heart, blending the best traits of two powerful breeds. Their calm, loyal nature and impressive stature make them cherished members of the family, providing security and affection. If you’re seeking a devoted companion with a majestic presence, the Daniff could be your perfect match!
Ray
Charlotte, North Carolina
Staci
Minnesota, Minnesota
